Entry Detail


General Information

Database ID:exR0510778
RNA Name:ABCD3
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):94418389End Site(bp):94518666
External Links:ENSG00000117528



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
SLC25A6
chrX
1386152
1392113
-
RPL13
chr16
89560657
89566828
+
ACYP2
chr2
53970838
54305300
+
RPL15
chr3
23916545
23924374
+
C18orf25
chr18
46173553
46266992
+
GFM1
chr3
158644278
158692575
+
SH3KBP1
chrX
19533977
19887600
-
EGLN2
chr19
40798996
40808434
+
MIF
chr22
23894383
23895227
+
LTA4H
chr12
96000753
96043520
-
RIC1
chr9
5629025
5776557
+
EIF3L
chr22
37848868
37889407
+
SMIM13
chr6
11093834
11138733
+
ZKSCAN8
chr6
28141883
28159460
+
NACA
chr12
56712427
56731628
-
CBX4
chr17
79833156
79839440
-
RPS6
chr9
19375715
19380236
-
HNRNPR
chr1
23303771
23344336
-
RPL28
chr19
55385345
55403250
+
MYCN
chr2
15940550
15947007
+
PELP1
chr17
4669774
4704337
-
HSP90AA1
chr14
102080738
102139699
-
GMPS
chr3
155870650
155944020
+
COPA
chr1
160288594
160343273
-
PLEKHO2
chr15
64841883
64868002
+
MAP2K4
chr17
12020829
12143830
+
LAPTM4B
chr8
97775057
97853013
+
RBX1
chr22
40951347
40973309
+
C11orf24
chr11
68261338
68272001
-
CRYL1
chr13
20403666
20525873
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL022311.1
chr22
37876148
37895563
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.