Entry Detail


General Information

Database ID:exR0510779
RNA Name:ABCD4
RNA Type:mRNA
Chromosome:chr14
Starnd:-
Coordinate:
Start Site(bp):74285269End Site(bp):74303055
External Links:ENSG00000119688



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
QSER1
chr11
32892820
32993316
+
MRPL46
chr15
88459477
88467390
-
MXRA8
chr1
1352689
1361777
-
NSUN2
chr5
6599239
6633291
-
M6PR
chr12
8940361
8949761
-
SIK1
chr21
43414483
43427131
-
RPL10
chrX
154389955
154409168
+
SFI1
chr22
31488688
31618588
+
C5orf24
chr5
134845680
134859735
+
RDH13
chr19
55039108
55071291
-
CRYL1
chr13
20403666
20525873
-
LONRF3
chrX
118974614
119018355
+
ORC3
chr6
87590067
87667453
+
ACOT8
chr20
45841721
45857405
-
TP53RK
chr20
46684365
46689444
-
ZNF668
chr16
31060843
31074240
-
PFN1
chr17
4945652
4949061
-
LTK
chr15
41503637
41513887
-
TOMM40L
chr1
161225939
161230746
+
FBXW4
chr10
101610664
101695295
-
NEO1
chr15
73051710
73305205
+
SELENOS
chr15
101270817
101277500
-
NHP2
chr5
178149460
178153967
-
EIF4H
chr7
74174245
74197101
+
HSP90AB1
chr6
44246166
44253888
+
BTBD2
chr19
1985438
2034881
-
TRIP13
chr5
892884
919357
+
HSPA4
chr5
133052013
133106449
+
CCDC167
chr6
37482938
37499893
-
VMP1
chr17
59707192
59842255
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005519.1
chr14
74289127
74294425
-
AC005562.1
chr17
30576464
30672789
+
AC007952.4
chr17
19112000
19112636
-
AC011476.2
chr19
55027593
55053928
-
MALAT1
chr11
65497688
65506516
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.