Entry Detail


General Information

Database ID:exR0510780
RNA Name:ABCE1
RNA Type:mRNA
Chromosome:chr4
Starnd:+
Coordinate:
Start Site(bp):145098288End Site(bp):145129524
External Links:ENSG00000164163



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MGST1
chr12
16347142
16609259
+
MTX2
chr2
176269395
176338025
+
RPL37A
chr2
216498825
216579180
+
FAM162A
chr3
122384176
122412334
+
ENOPH1
chr4
82430590
82461177
+
ANKRD17
chr4
73073376
73258798
-
SLC25A29
chr14
100291116
100306547
-
INSIG1
chr7
155297776
155310235
+
LAMTOR1
chr11
72085895
72103297
-
GNB5
chr15
52115105
52191369
-
IVNS1ABP
chr1
185296388
185317273
-
TIMMDC1
chr3
119498547
119525090
+
HOXA3
chr7
27106184
27152581
-
STMN1
chr1
25884181
25906991
-
UGP2
chr2
63840940
63891562
+
RPL3
chr22
39312882
39320389
-
PGK1
chrX
77910739
78129295
+
RBL2
chr16
53433977
53491648
+
BCAT1
chr12
24810024
24949101
-
RPS23
chr5
82273320
82278396
-
TNPO2
chr19
12699194
12724011
-
TUBB
chr6
30720352
30725426
+
CHTF8
chr16
69118010
69132578
-
CLPTM1L
chr5
1317752
1345099
-
RAB10
chr2
26034084
26137454
+
MDH2
chr7
76048051
76067508
+
CREBZF
chr11
85659708
85682908
-
C19orf48
chr19
50797704
50804929
-
EWSR1
chr22
29268009
29300525
+
ATP5MG
chr11
118401606
118431496
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL157871.6
chr14
100279959
100291456
-
FAM215B
chr17
46558830
46562795
-
MAPKAPK5-AS1
chr12
111839764
111842902
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.