Entry Detail


General Information

Database ID:exR0510782
RNA Name:ABCF2
RNA Type:mRNA
Chromosome:chr7
Starnd:-
Coordinate:
Start Site(bp):151207837End Site(bp):151227166
External Links:ENSG00000285292



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
COX7C
chr5
86617928
86620962
+
ABCF2
chr7
151207837
151227166
-
EIF3L
chr22
37848868
37889407
+
PROM1
chr4
15963076
16084378
-
MTG1
chr10
133394094
133422520
+
SPG11
chr15
44562696
44663678
-
SUV39H2
chr10
14878820
14904315
+
MAP4
chr3
47850690
48089272
-
BTBD2
chr19
1985438
2034881
-
TRAPPC12
chr2
3379675
3485094
+
DYNLL2
chr17
58083419
58095542
+
IL32
chr16
3065297
3082192
+
STAT5B
chr17
42199177
42276707
-
RPS4X
chrX
72255679
72277248
-
MCOLN1
chr19
7522624
7534009
+
OST4
chr2
27070472
27071654
-
SERPINE1
chr7
101127104
101139247
+
CCT4
chr2
61868085
61888671
-
ENO1
chr1
8861000
8879190
-
ELOVL5
chr6
53267398
53349179
-
CD164
chr6
109366514
109382467
-
SLC37A4
chr11
119024114
119030906
-
AL360181.3
chr10
133380017
133420271
+
PHIP
chr6
78934419
79078254
-
LPGAT1
chr1
211743457
211830763
-
BCAT2
chr19
48795062
48811029
-
UBB
chr17
16380798
16382745
+
ERMP1
chr9
5765076
5833117
-
UBE2Q1
chr1
154548577
154559028
-
SNRNP40
chr1
31259568
31296788
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-107
chr10
89592756
89592778
-
hsa-miR-625-5p
chr14
65471116
65471136
+
hsa-miR-423-5p
chr17
30117095
30117117
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005487.1
chr7
108598352
108639349
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.