Entry Detail


General Information

Database ID:exR0510783
RNA Name:ABCF3
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):184186023End Site(bp):184194012
External Links:ENSG00000161204



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
STARD10
chr11
72754729
72793681
-
TRIOBP
chr22
37697048
37776556
+
ABCF2
chr7
151207837
151227166
-
AFDN
chr6
167826922
167972023
+
MBD5
chr2
148021011
148516971
+
RARB
chr3
25174332
25597932
+
EPN3
chr17
50532682
50543750
+
TPI1
chr12
6867119
6870948
+
PPP1R16B
chr20
38805697
38923024
+
MATR3
chr5
139273752
139331671
+
RAB43
chr3
129087569
129122801
-
EXOC7
chr17
76081016
76121576
-
SSR4
chrX
153793516
153798499
+
RPS19
chr19
41860255
41872925
+
ZEB2
chr2
144364364
144521057
-
HOXD3
chr2
176136612
176173102
+
KRR1
chr12
75490863
75511636
-
LIG3
chr17
34980512
35009743
+
Z83844.1
chr22
37686414
37726503
+
RPL13
chr16
89560657
89566828
+
SNRPG
chr2
70281362
70293740
-
EEF1A1
chr6
73515750
73523797
-
PDCD7
chr15
65117379
65133808
-
MAPKAP1
chr9
125437393
125707234
-
RPS6
chr9
19375715
19380236
-
GGA3
chr17
75236599
75262363
-
RERE
chr1
8352397
8848921
-
SAT1
chrX
23783173
23786226
+
MTRNR2L12
chr3
96617188
96618236
-
MARCKSL1
chr1
32333839
32336233
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-15a-5p
chr13
50049167
50049188
-
hsa-miR-15b-5p
chr3
160404607
160404628
+
hsa-miR-34c-5p
chr11
111513451
111513473
+
hsa-miR-497-5p
chr17
7017979
7017999
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016949.1
chr3
196912646
196914579
+
AL355075.4
chr14
20343048
20343685
-
LINC00858
chr10
84267747
84294659
+
RMRP
chr9
35657751
35658018
-
SRRM2-AS1
chr16
2737076
2752600
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.