Entry Detail


General Information

Database ID:exR0510785
RNA Name:ABCG2
RNA Type:mRNA
Chromosome:chr4
Starnd:-
Coordinate:
Start Site(bp):88090150End Site(bp):88231628
External Links:ENSG00000118777



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
PTMS
chr12
6765516
6770952
+
AP2B1
chr17
35578046
35726413
+
PFN1
chr17
4945652
4949061
-
ACKR3
chr2
236567787
236582354
+
RFX5
chr1
151340640
151347357
-
SUPT16H
chr14
21351476
21384019
-
ABHD14A-ACY1
chr3
51974706
51989183
+
PLXNA2
chr1
208022242
208244384
-
PDXDC1
chr16
14974591
15139339
+
SDC2
chr8
96493813
96611790
+
MORN3
chr12
121648742
121672631
-
RARB
chr3
25174332
25597932
+
GNPDA1
chr5
141991749
142013041
-
TPT1
chr13
45333471
45341370
-
ZNRF2
chr7
30284597
30367689
+
PSMA5
chr1
109399042
109426448
-
ELF1
chr13
40931924
41061440
-
PDHB
chr3
58427630
58433857
-
PSMA4
chr15
78540405
78552417
+
CCND3
chr6
41934933
42050357
-
NELFA
chr4
1982717
2041903
-
RPS3
chr11
75399515
75422280
+
MTRNR2L12
chr3
96617188
96618236
-
NMD3
chr3
161104696
161253532
+
UGT3A2
chr5
36035021
36071358
-
AFF4
chr5
132875395
132963634
-
HNRNPA2B1
chr7
26173057
26201529
-
CDH1
chr16
68737292
68835541
+
SIPA1L1
chr14
71320449
71741229
+
RPL9
chr4
39452521
39458949
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC078881.1
chr4
177442519
177681381
+
AC069287.1
chr11
112967
125927
-
NR2F1-AS1
chr5
93360779
93585649
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.