Entry Detail


General Information

Database ID:exR0510792
RNA Name:ABHD12
RNA Type:mRNA
Chromosome:chr20
Starnd:-
Coordinate:
Start Site(bp):25294742End Site(bp):25390835
External Links:ENSG00000100997



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
NAT8L
chr4
2059327
2069089
+
MAN2A1
chr5
109689366
109869625
+
CUTC
chr10
99702558
99756134
+
ERAL1
chr17
28855010
28861061
+
HMOX1
chr22
35380361
35394207
+
MSL2
chr3
136148917
136197241
-
ERBB2
chr17
39687914
39730426
+
RPL8
chr8
144789765
144792587
-
MX1
chr21
41420304
41459214
+
ACP6
chr1
147629652
147670524
-
SIRT6
chr19
4174109
4182566
-
LSM7
chr19
2321520
2328611
-
PDCD2L
chr19
34404399
34426168
+
TPX2
chr20
31739271
31801805
+
ZNF764
chr16
30553764
30558498
-
TSPAN3
chr15
77041404
77083984
-
CXADR
chr21
17513043
17593579
+
ARIH2
chr3
48918821
48986382
+
RBM27
chr5
146203605
146289223
+
GINS1
chr20
25407673
25452628
+
UBE2J1
chr6
89326625
89352722
-
RBM22
chr5
150690792
150701077
-
EEF2
chr19
3976056
3985463
-
MED16
chr19
867630
893218
-
CYB5R3
chr22
42617840
42649392
-
PHIP
chr6
78934419
79078254
-
RBFA
chr18
80034389
80050651
+
EIF2S2
chr20
34088309
34112243
-
FKBP10
chr17
41812680
41823213
+
EML4
chr2
42169353
42332548
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012236.1
chr15
31221999
31230838
-
AD000090.1
chr19
35557956
35581954
+
AL135925.1
chr10
79825902
79827602
+
SNHG22
chr18
49814023
49851059
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.