Entry Detail


General Information

Database ID:exR0510808
RNA Name:ABL1
RNA Type:mRNA
Chromosome:chr9
Starnd:+
Coordinate:
Start Site(bp):130713016End Site(bp):130887675
External Links:ENSG00000097007



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CXCL12
chr10
44370165
44386493
-
ASXL2
chr2
25733753
25878487
-
TMEM115
chr3
50354750
50359521
-
STK11
chr19
1177558
1228431
+
TMEM214
chr2
27032910
27041694
+
NOP53
chr19
47745546
47757058
+
TSC2
chr16
2047967
2089491
+
CHTOP
chr1
153633982
153646306
+
ZMYM3
chrX
71239624
71255146
-
NUTF2
chr16
67846923
67872567
+
DBNDD2
chr20
45406057
45410610
+
PCGF2
chr17
38733898
38749817
-
TM9SF3
chr10
96518110
96587452
-
CHD4
chr12
6570082
6614524
-
AP000350.4
chr22
23862188
23895223
+
PLCG1
chr20
41136960
41196801
+
ACTB
chr7
5527148
5563784
-
ATE1
chr10
121740421
121928801
-
TSPAN6
chrX
100627108
100639991
-
TRAF2
chr9
136881912
136926607
+
HMGN4
chr6
26538366
26546933
+
ETS2
chr21
38805183
38824955
+
LAMP5
chr20
9514358
9530524
+
MOV10
chr1
112673141
112700746
+
GLUL
chr1
182381704
182392206
-
TPM4
chr19
16067021
16103002
+
SIGIRR
chr11
405716
417455
-
HNRNPD
chr4
82352498
82374503
-
CORO7
chr16
4354542
4425705
-
ZNF319
chr16
57994668
58000453
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-432-5p
chr14
100884496
100884518
+
hsa-miR-520a-5p
chr19
53690895
53690915
+
hsa-miR-650
chr22
22822791
22822811
+
hsa-miR-330-5p
chr19
45639049
45639070
-
hsa-miR-760
chr1
93846880
93846899
+
hsa-miR-1270
chr19
20399320
20399342
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007993.3
chr17
43914433
43923001
-
AC069281.2
chr7
100572232
100578700
-
NEAT1
chr11
65422774
65445540
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.