Entry Detail


General Information

Database ID:exR0510831
RNA Name:ACAP1
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):7336529End Site(bp):7351477
External Links:ENSG00000072818



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HLA-DRA
chr6
32439878
32445046
+
FOXH1
chr8
144473412
144475849
-
ZNF449
chrX
135344796
135363413
+
MIF
chr22
23894383
23895227
+
KDF1
chr1
26949562
26960468
-
SQSTM1
chr5
179806398
179838078
+
PFN1
chr17
4945652
4949061
-
CD74
chr5
150400041
150412929
-
RGS10
chr10
119499817
119542719
-
TUBB
chr6
30720352
30725426
+
ISG15
chr1
1001138
1014540
+
C20orf204
chr20
64034344
64039962
+
AL133352.1
chr10
100505628
100529881
-
DHX16
chr6
30653119
30673006
-
AP002990.1
chr11
62559603
62591531
-
UGCG
chr9
111896814
111935369
+
DNAJC30
chr7
73680918
73683453
-
ACTG1
chr17
81509971
81523847
-
VPS53
chr17
508668
721717
-
HLA-DMA
chr6
32948613
32969094
-
CDC25B
chr20
3786772
3806121
+
RCC1
chr1
28505943
28539300
+
YME1L1
chr10
27110112
27155266
-
REEP3
chr10
63521401
63625128
+
CD70
chr19
6583183
6604103
-
ZNF593
chr1
26169908
26170873
+
NSMF
chr9
137447573
137459334
-
EXOC3
chr5
443175
471937
+
ZNF761
chr19
53445001
53458261
+
APH1A
chr1
150265399
150269580
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC139149.1
chr17
81514047
81527776
+
LINC01184
chr5
127939152
128083172
-
SNHG3
chr1
28505980
28510892
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.