Entry Detail


General Information

Database ID:exR0510836
RNA Name:ACBD4
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):45132600End Site(bp):45144181
External Links:ENSG00000181513



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ANP32A
chr15
68778535
68820897
-
BSG
chr19
571277
583493
+
CCDC6
chr10
59788747
59906556
-
CDON
chr11
125955796
126063335
-
DYNLL2
chr17
58083419
58095542
+
EIF3C
chr16
28688558
28735730
+
ENO1
chr1
8861000
8879190
-
GAPDH
chr12
6534512
6538374
+
GATAD1
chr7
92447482
92460075
+
HPN
chr19
35040506
35066571
+
KAT7
chr17
49788681
49835026
+
LIN28A
chr1
26410817
26429728
+
LRP4
chr11
46856717
46918642
-
MAD2L2
chr1
11674480
11691650
-
PDE4D
chr5
58969038
60522120
-
PDHB
chr3
58427630
58433857
-
PPP6R1
chr19
55229779
55259017
-
SCAND1
chr20
35953617
35959472
-
TMA16
chr4
163494442
163520539
+
TPM3
chr1
154155304
154194648
-
TPRN
chr9
137191617
137204193
-
TSR1
chr17
2322396
2336657
-
TUBA1B
chr12
49127782
49131397
-
USP39
chr2
85602856
85649283
+
VPS26C
chr21
37223420
37267919
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC027290.2
chr12
122865335
122867021
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.