Entry Detail


General Information

Database ID:exR0510837
RNA Name:ACBD5
RNA Type:mRNA
Chromosome:chr10
Starnd:-
Coordinate:
Start Site(bp):27195214End Site(bp):27242130
External Links:ENSG00000107897



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CDC42SE1
chr1
151050971
151070325
-
MAML3
chr4
139716753
140154184
-
TUBA1C
chr12
49188736
49274603
+
RPL13A
chr19
49487554
49492308
+
MAP4K2
chr11
64784918
64803241
-
PTCD1
chr7
99416739
99466163
-
ATP5MF-PTCD1
chr7
99419749
99466197
-
HSPA8
chr11
123057489
123063230
-
GGA2
chr16
23463542
23521995
-
TUBA1A
chr12
49184795
49189080
-
TMEM216
chr11
61392360
61398863
+
YLPM1
chr14
74763316
74859435
+
AMOT
chrX
112774503
112840815
-
IGF2
chr11
2129112
2141238
-
PLS1
chr3
142596393
142713664
+
DECR2
chr16
401858
412487
+
TPI1
chr12
6867119
6870948
+
RNF7
chr3
141738249
141747560
+
ENO1
chr1
8861000
8879190
-
RTN3
chr11
63681446
63759891
+
MYL12B
chr18
3261479
3278431
+
B2M
chr15
44711487
44718877
+
LRIG2
chr1
113073198
113132260
+
CKAP5
chr11
46743048
46846308
-
RPS24
chr10
78033760
78056813
+
GOT2
chr16
58707131
58734342
-
HIPK3
chr11
33256672
33357023
+
FTL
chr19
48965309
48966879
+
LCP1
chr13
46125920
46211871
-
NACA2
chr17
61590421
61591219
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-93-5p
chr7
100093815
100093837
-
hsa-miR-145-5p
chr5
149430661
149430683
+
hsa-miR-526b-5p
chr19
53694406
53694428
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC020916.1
chr19
13823880
13842928
-
AC132217.1
chr11
2129121
2129964
-
SNHG1
chr11
62851984
62855953
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.