Entry Detail


General Information

Database ID:exR0510853
RNA Name:ACO2
RNA Type:mRNA
Chromosome:chr22
Starnd:+
Coordinate:
Start Site(bp):41469117End Site(bp):41528989
External Links:ENSG00000100412



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
RASA4
chr7
102573807
102616757
-
NOC2L
chr1
944203
959309
-
RPS17
chr15
82536750
82540459
-
LAMA1
chr18
6941742
7117797
-
DPYSL2
chr8
26514031
26658178
+
MTIF2
chr2
55236595
55269347
-
EDIL3
chr5
83940554
84384880
-
NAMPT
chr7
106248298
106286326
-
CDH1
chr16
68737292
68835541
+
AP002990.1
chr11
62559603
62591531
-
DDX19B
chr16
70289663
70335283
+
IFITM1
chr11
313506
315272
+
COMT
chr22
19941733
19969975
+
R3HDM2
chr12
57253762
57431005
-
HNRNPK
chr9
83968083
83980616
-
TMBIM6
chr12
49707725
49764934
+
TUBB
chr6
30720352
30725426
+
U2AF1L5
chr21
6484623
6499261
-
WDR74
chr11
62832342
62841809
-
IQCB1
chr3
121769761
121835079
-
KIF26A
chr14
104138723
104180894
+
CDCA2
chr8
25459199
25507911
+
RRP36
chr6
43021623
43034156
+
PTPRS
chr19
5158495
5340803
-
HDGFL3
chr15
83112738
83207823
-
DAP
chr5
10679230
10761272
-
CD52
chr1
26317958
26320523
+
PSMA2
chr7
42916861
42932185
-
COPG1
chr3
129249606
129277773
+
FRMPD4
chrX
11822423
12724523
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC079781.5
chr7
97851688
97972985
-
AC147651.4
chr7
603185
608482
+
AC245033.4
chr15
82533175
82540008
-
SNHG19
chr16
2154797
2155358
-
SNHG7
chr9
136721366
136728184
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.