Entry Detail


General Information

Database ID:exR0510861
RNA Name:ACOT8
RNA Type:mRNA
Chromosome:chr20
Starnd:-
Coordinate:
Start Site(bp):45841721End Site(bp):45857405
External Links:ENSG00000101473



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BAHD1
chr15
40439721
40468236
+
RPS14
chr5
150442635
150449739
-
C19orf53
chr19
13774456
13778773
+
B2M
chr15
44711487
44718877
+
CHST15
chr10
124007668
124093598
-
HAUS7
chrX
153447666
153495516
-
CANX
chr5
179678628
179731641
+
SRPK2
chr7
105110704
105399308
-
SZRD1
chr1
16352575
16398145
+
CCL3
chr17
36088256
36090169
-
HVCN1
chr12
110627841
110704950
-
MAP7D1
chr1
36155579
36180849
+
VMP1
chr17
59707192
59842255
+
NCF4
chr22
36860988
36878017
+
WBP1
chr2
74458400
74460891
+
SBK1
chr16
28259246
28323849
+
SLC16A1
chr1
112911847
112957013
-
ARPC4
chr3
9792495
9807726
+
CIC
chr19
42268537
42295797
+
PPP2R5C
chr14
101761798
101927989
+
CDK2
chr12
55966781
55972789
+
GCSAM
chr3
112120839
112133270
-
EP400
chr12
131949942
132080460
+
ABCD4
chr14
74285269
74303055
-
RPL27A
chr11
8682788
8714759
+
PYURF
chr4
88520998
88523776
-
SAP18
chr13
21140514
21149084
+
H6PD
chr1
9234775
9271337
+
NOP53
chr19
47745546
47757058
+
TRIM45
chr1
117111060
117122587
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
BX890604.2
chrX
3817528
3937855
-
MALAT1
chr11
65497688
65506516
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.