Entry Detail


General Information

Database ID:exR0510862
RNA Name:ACOT9
RNA Type:mRNA
Chromosome:chrX
Starnd:-
Coordinate:
Start Site(bp):23701055End Site(bp):23766475
External Links:ENSG00000123130



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CALM2
chr2
47160083
47176921
-
NKX1-2
chr10
124445243
124450035
-
PKP3
chr11
392614
404908
+
GDI2
chr10
5765223
5842132
-
RPLP1
chr15
69452814
69456205
+
TTLL3
chr3
9808086
9855138
+
KPNA5
chr6
116681187
116741867
+
PKN2
chr1
88684222
88836255
+
PLEKHB2
chr2
131104847
131353709
+
AIP
chr11
67483026
67491103
+
MT-CO2
chrMT
7586
8269
+
NUP155
chr5
37288137
37371106
-
PIEZO1
chr16
88715338
88785220
-
N4BP2L2
chr13
32432417
32538885
-
OCLN
chr5
69492292
69558104
+
CEP55
chr10
93496612
93529092
+
HLA-C
chr6
31268749
31272130
-
PNPO
chr17
47941506
47949308
+
MYDGF
chr19
4641374
4670362
-
SSBP1
chr7
141738334
141787922
+
NECAP2
chr1
16440721
16460078
+
RPS16
chr19
39433137
39435949
-
HMGCS1
chr5
43287470
43313512
-
DICER1
chr14
95086228
95158010
-
ANKRD46
chr8
100509752
100559784
-
PCBP1
chr2
70087477
70089203
+
PHTF2
chr7
77798792
77957503
+
RGS1
chr1
192575763
192580024
+
ADNP
chr20
50888916
50931437
-
CD74
chr5
150400041
150412929
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
JPX
chrX
73944182
74070408
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.