Entry Detail


General Information

Database ID:exR0510865
RNA Name:ACOX3
RNA Type:mRNA
Chromosome:chr4
Starnd:-
Coordinate:
Start Site(bp):8366282End Site(bp):8440723
External Links:ENSG00000087008



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AFAP1
chr4
7758714
7939926
-
COX4I1
chr16
85798633
85807068
+
COX7C
chr5
86617928
86620962
+
DOCK10
chr2
224765090
225042445
-
HADH
chr4
107989714
108035175
+
HSPA9
chr5
138553756
138575416
-
IFI6
chr1
27666064
27672198
-
INTS10
chr8
19817391
19852083
+
LRRC1
chr6
53794497
53924125
+
MUTYH
chr1
45329163
45340893
-
PABPC1
chr8
100685816
100722809
-
PCBP1
chr2
70087477
70089203
+
RACK1
chr5
181236897
181248096
-
SERGEF
chr11
17788048
18013047
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC055860.1
chr11
18000542
18022931
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.