Entry Detail


General Information

Database ID:exR0510867
RNA Name:ACP1
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):264140End Site(bp):278283
External Links:ENSG00000143727



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
PIP4K2A
chr10
22534854
22714578
-
XPO6
chr16
28097979
28211920
-
UBP1
chr3
33388336
33441371
-
CST3
chr20
23626706
23638473
-
RPS4X
chrX
72255679
72277248
-
ENSA
chr1
150600851
150629612
-
PTOV1
chr19
49850735
49860744
+
SMC5
chr9
70258978
70354873
+
TUFM
chr16
28842411
28846348
-
DTD2
chr14
31446036
31457506
-
B2M
chr15
44711487
44718877
+
NUDT5
chr10
12165330
12196144
-
SCD
chr10
100347233
100364826
+
VSIG10
chr12
118063593
118136026
-
TBX6
chr16
30085793
30091887
-
AC009133.6
chr16
29812261
29820092
+
BORCS5
chr12
12357078
12471233
+
ARPC2
chr2
218217141
218254356
+
TOP2A
chr17
40388525
40417896
-
MT-CO1
chrMT
5904
7445
+
EIF3CL
chr16
28379579
28403879
-
EIF3H
chr8
116642130
116766925
-
POLH
chr6
43576185
43620523
+
TUBB
chr6
30720352
30725426
+
CHMP1A
chr16
89644435
89657721
-
MOB3A
chr19
2071036
2096673
-
LYRM4
chr6
5102593
5260939
-
TP53
chr17
7661779
7687550
-
ORMDL3
chr17
39921041
39927601
-
MSH2
chr2
47403067
47663146
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-let-7b-5p
chr22
46113691
46113712
+
hsa-let-7d-5p
chr9
94178841
94178862
+
hsa-let-7f-5p
chrX
53557246
53557267
-
hsa-miR-196a-5p
chr17
48632532
48632553
-
hsa-let-7g-5p
chr3
52268336
52268357
-
hsa-let-7i-5p
chr12
62603691
62603712
+
hsa-miR-151a-3p
chr8
140732587
140732607
-
hsa-miR-196b-5p
chr7
27169528
27169549
-
hsa-miR-519c-5p
chr19
53686484
53686505
+
hsa-miR-519b-5p
chr19
53695225
53695246
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC126365.1
chr17
20788071
20789584
+
AL139819.1
chr10
100335563
100346390
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.