Entry Detail


General Information

Database ID:exR0510870
RNA Name:ACPP
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):132317369End Site(bp):132368298
External Links:ENSG00000014257



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC120057.2
chr17
7240427
7244635
-
ADGRA3
chr4
22345071
22516066
-
AGTRAP
chr1
11736084
11754802
+
CHTOP
chr1
153633982
153646306
+
CLCN3
chr4
169612633
169723673
+
G3BP1
chr5
151771045
151812785
+
GABARAP
chr17
7240008
7242449
-
LZIC
chr1
9922113
9943407
-
NUDT16L1
chr16
4693694
4695859
+
OTUD5
chrX
48922028
48958386
-
PPIA
chr7
44796680
44824564
+
RPL13
chr16
89560657
89566828
+
RPL14
chr3
40457292
40468587
+
SAFB
chr19
5623035
5668478
+
SRSF1
chr17
58000919
58007346
-
STC2
chr5
173314713
173329503
-
TFG
chr3
100709331
100748964
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.