Entry Detail


General Information

Database ID:exR0510875
RNA Name:ACSF3
RNA Type:mRNA
Chromosome:chr16
Starnd:+
Coordinate:
Start Site(bp):89088375End Site(bp):89164121
External Links:ENSG00000176715



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
REXO1
chr19
1815248
1848483
-
PBX1
chr1
164555584
164899296
+
RBFOX2
chr22
35738736
36028824
-
FAM193B
chr5
177519789
177554563
-
SLC47A1
chr17
19495385
19579034
+
ATG2A
chr11
64894546
64917211
-
TP63
chr3
189631389
189897276
+
ARID1A
chr1
26693236
26782104
+
SBNO2
chr19
1107637
1174268
-
AKT2
chr19
40230317
40285536
-
LRRC14
chr8
144517992
144525172
+
DGKD
chr2
233354507
233472104
+
SATB1
chr3
18345377
18445588
-
DCTD
chr4
182890060
182917936
-
NHSL1
chr6
138422043
138692571
-
SOX4
chr6
21593751
21598619
+
ZNF227
chr19
44207547
44237268
+
FAM189B
chr1
155247205
155255483
-
PAK4
chr19
39125770
39182816
+
SNRPB
chr20
2461634
2470853
-
RPL18A
chr19
17859910
17864153
+
NDUFV2
chr18
9102630
9134345
+
ABR
chr17
1003518
1229738
-
TANGO2
chr22
20017014
20067164
+
BPTF
chr17
67825503
67984378
+
UBA52
chr19
18571730
18577550
+
SYAP1
chrX
16719612
16765340
+
ADAR
chr1
154582057
154628013
-
TXNL1
chr18
56597209
56651600
-
NUP153
chr6
17615035
17706834
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AP005263.1
chr18
9102736
9254346
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.