Entry Detail


General Information

Database ID:exR0510876
RNA Name:ACSL1
RNA Type:mRNA
Chromosome:chr4
Starnd:-
Coordinate:
Start Site(bp):184755595End Site(bp):184826818
External Links:ENSG00000151726



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACOT7
chr1
6264269
6394391
-
ACP6
chr1
147629652
147670524
-
ALMS1
chr2
73385758
73625166
+
APOBEC3G
chr22
39077067
39087743
+
BCAT2
chr19
48795062
48811029
-
CCL22
chr16
57358783
57366189
+
CHST12
chr7
2403588
2448484
+
CPNE1
chr20
35626031
35664956
-
DDB1
chr11
61299451
61342596
-
DPYSL2
chr8
26514031
26658178
+
ENOSF1
chr18
670318
712662
-
FADS2
chr11
61792980
61867354
+
FBL
chr19
39834458
39846379
-
HNRNPH1
chr5
179614178
179634784
-
IMP3
chr15
75639085
75648706
-
LPXN
chr11
58526871
58578220
-
NAA16
chr13
41311267
41377030
+
POLL
chr10
101578882
101588270
-
PTDSS2
chr11
448268
491399
+
TMEM170A
chr16
75443054
75465497
-
TWNK
chr10
100987367
100994403
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-34a-5p
chr1
9151735
9151756
-
hsa-miR-205-5p
chr1
209432166
209432187
+
hsa-miR-34c-5p
chr11
111513451
111513473
+
hsa-miR-337-3p
chr14
100874553
100874574
+
hsa-miR-449a
chr5
55170586
55170607
-
hsa-miR-449b-5p
chr5
55170706
55170727
-
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.