Entry Detail


General Information

Database ID:exR0510877
RNA Name:ACSL3
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):222860942End Site(bp):222944639
External Links:ENSG00000123983



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BCORL1
chrX
129981107
130058083
+
GANAB
chr11
62624826
62646726
-
TMA7
chr3
48440257
48444208
+
TPMT
chr6
18128311
18155077
-
EIF1B
chr3
40309707
40312424
+
AIFM1
chrX
130129362
130165887
-
IRX3
chr16
54283304
54286787
-
OTUD1
chr10
23439458
23442390
+
VASN
chr16
4371848
4383538
+
TTC37
chr5
95461755
95555007
-
EP300
chr22
41092592
41180077
+
NSUN4
chr1
46340177
46365152
+
MED1
chr17
39404285
39451272
-
MAGT1
chrX
77826364
77895593
-
EEF2
chr19
3976056
3985463
-
ZWILCH
chr15
66504959
66550130
+
RPL7L1
chr6
42879616
42889925
+
AP001781.2
chr11
111786286
111879425
-
RPS7
chr2
3575260
3580920
+
TUBA1A
chr12
49184795
49189080
-
SMARCC1
chr3
47585269
47782106
-
DDX39B
chr6
31530219
31542448
-
IQSEC1
chr3
12897043
13283281
-
DBN1
chr5
177456608
177474401
-
MRFAP1
chr4
6640091
6642745
+
ISCA1
chr9
86264546
86283102
-
GNA12
chr7
2728105
2844308
-
INTS13
chr12
26905181
26938326
-
DMXL2
chr15
51447711
51622833
-
CD47
chr3
108043091
108091862
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010733.2
chr2
60925909
60931610
+
AC245033.2
chr15
82540870
82562374
+
LINC00836
chr10
25651712
25732935
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.