Entry Detail


General Information

Database ID:exR0510878
RNA Name:ACSL4
RNA Type:mRNA
Chromosome:chrX
Starnd:-
Coordinate:
Start Site(bp):109624244End Site(bp):109733403
External Links:ENSG00000068366



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CEP78
chr9
78236062
78279690
+
RPL23
chr17
38847860
38853764
-
ADGRL1
chr19
14147743
14206187
-
LRBA
chr4
150264435
151015727
-
ACOT2
chr14
73567620
73575658
+
COX8A
chr11
63974620
63976543
+
PITPNC1
chr17
67377281
67697261
+
BEX5
chrX
102153708
102155977
-
NUDT21
chr16
56429133
56452199
-
NUCKS1
chr1
205712822
205750182
-
BHLHE40
chr3
4979437
4985323
+
ZMYM4
chr1
35268709
35422058
+
KCNE5
chrX
109623700
109625172
-
C9orf40
chr9
74946583
74952912
-
CPZ
chr4
8592660
8619759
+
MZT2A
chr2
131464900
131492743
-
ENO1
chr1
8861000
8879190
-
ARPC5
chr1
183620846
183635783
-
ZMAT2
chr5
140698680
140706686
+
MKNK2
chr19
2037465
2051244
-
MTRNR2L1
chr17
22523111
22524663
+
HELQ
chr4
83407343
83455855
-
GAPDH
chr12
6534512
6538374
+
FOXRED1
chr11
126269055
126278131
+
KRAS
chr12
25205246
25250936
-
TIMM17B
chrX
48893447
48898143
-
COPB2
chr3
139355600
139389680
-
UBL7
chr15
74445977
74461182
-
CDS2
chr20
5126879
5197887
+
EFTUD2
chr17
44849948
44899445
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-34a-5p
chr1
9151735
9151756
-
hsa-miR-34c-5p
chr11
111513451
111513473
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC106864.1
chr4
112693047
112706810
-
AL117378.1
chr6
131901963
131920565
+
AP003175.1
chr11
75069243
75096964
-
NEAT1
chr11
65422774
65445540
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.