Entry Detail


General Information

Database ID:exR0510887
RNA Name:ACSS2
RNA Type:mRNA
Chromosome:chr20
Starnd:+
Coordinate:
Start Site(bp):34872146End Site(bp):34927962
External Links:ENSG00000131069



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
RPS19
chr19
41860255
41872925
+
TUBA1B
chr12
49127782
49131397
-
VPS26B
chr11
134224671
134247788
+
EIF6
chr20
35278911
35284985
-
KIAA0930
chr22
45190338
45240769
-
KLHDC4
chr16
87696485
87765992
-
TXNL4A
chr18
79970813
80033949
-
TUBA1A
chr12
49184795
49189080
-
NDUFB1
chr14
92116122
92121917
-
DUT
chr15
48331011
48343373
+
NUCKS1
chr1
205712822
205750182
-
SIK3
chr11
116843402
117098437
-
COPS7B
chr2
231781671
231809254
+
LMBR1
chr7
156668946
156893216
-
PFN1
chr17
4945652
4949061
-
SLC52A3
chr20
760080
776015
-
BLOC1S4
chr4
6716174
6717664
+
GDI2
chr10
5765223
5842132
-
DDX5
chr17
64498254
64508199
-
TPI1
chr12
6867119
6870948
+
KXD1
chr19
18557762
18569387
+
NDUFS7
chr19
1383527
1395589
+
DPF2
chr11
65333852
65354262
+
AL121753.1
chr20
35267885
35280043
-
STAT5B
chr17
42199177
42276707
-
RPS11
chr19
49496365
49499708
+
DYNLL1
chr12
120469850
120498493
+
PPP6R1
chr19
55229779
55259017
-
STAU1
chr20
49113339
49188367
-
HSP90AB1
chr6
44246166
44253888
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-18a-5p
chr13
91350756
91350778
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL022311.1
chr22
37876148
37895563
+
AL022332.1
chr22
25279529
25282674
-
GAS5
chr1
173858559
173868882
-
LINC01405
chr12
110934590
110959093
+
MIR17HG
chr13
91347820
91354579
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.