Entry Detail


General Information

Database ID:exR0510888
RNA Name:ACSS3
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):80936414End Site(bp):81261210
External Links:ENSG00000111058



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
TRAM1L1
chr4
117083554
117085576
-
NMNAT2
chr1
183248237
183418380
-
EPB41L2
chr6
130839347
131063322
-
CNST
chr1
246566444
246668595
+
TJP1
chr15
29699367
29968865
-
UBL7
chr15
74445977
74461182
-
SENP3-EIF4A1
chr17
7563287
7578715
+
UBE2E1
chr3
23805955
23891640
+
MIDN
chr19
1248553
1259140
+
TUBB
chr6
30720352
30725426
+
KXD1
chr19
18557762
18569387
+
U2SURP
chr3
142964497
143060725
+
TPI1
chr12
6867119
6870948
+
UBE2D2
chr5
139526431
139628434
+
SCAPER
chr15
76347904
76905444
-
PTGES3
chr12
56663341
56688408
-
DEK
chr6
18223860
18264548
-
OPRD1
chr1
28812142
28871267
+
POLR1D
chr13
27620742
27744237
+
RPS23
chr5
82273320
82278396
-
EIF4A1
chr17
7572706
7579006
+
RHEB
chr7
151466012
151520120
-
RPS6KC1
chr1
213051233
213274774
+
ME2
chr18
50879080
50954257
+
ARF4
chr3
57571363
57598220
-
ENO1
chr1
8861000
8879190
-
SWT1
chr1
185157080
185291781
+
CRABP2
chr1
156699606
156705816
-
NONO
chrX
71283192
71301168
+
HMGN4
chr6
26538366
26546933
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
NIFK-AS1
chr2
121649320
121728563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.