Entry Detail


General Information

Database ID:exR0510904
RNA Name:ACTR1B
RNA Type:mRNA
Chromosome:chr2
Starnd:-
Coordinate:
Start Site(bp):97655939End Site(bp):97664044
External Links:ENSG00000115073



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
TEDC2
chr16
2460086
2464963
+
COMMD1
chr2
61888724
62147247
+
SDC2
chr8
96493813
96611790
+
SND1
chr7
127652194
128092609
+
RAB11A
chr15
65726054
65891989
+
ACTG1
chr17
81509971
81523847
-
PCBP1
chr2
70087477
70089203
+
WRAP73
chr1
3630767
3652761
-
ACTA1
chr1
229431245
229434098
-
SNURF
chr15
24954986
24977850
+
PIK3C2B
chr1
204422628
204494724
-
KEAP1
chr19
10486125
10503558
-
GAPDH
chr12
6534512
6538374
+
GSTP1
chr11
67583742
67586656
+
POTEE
chr2
131218067
131265278
+
KCTD2
chr17
75032575
75065889
+
YLPM1
chr14
74763316
74859435
+
MTRNR2L12
chr3
96617188
96618236
-
MFSD2B
chr2
24010081
24063321
+
PGAM1
chr10
97426191
97433444
+
BAG6
chr6
31639028
31652705
-
PTMA
chr2
231706895
231713541
+
PSMB1
chr6
170535120
170553307
-
PLXNB2
chr22
50274979
50307646
-
RPN1
chr3
128619969
128681075
-
ZNF106
chr15
42412823
42491141
-
CLNS1A
chr11
77514936
77637794
-
ABLIM1
chr10
114431113
114768061
-
AL136295.5
chr14
24147548
24166452
+
EWSR1
chr22
29268009
29300525
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC008555.1
chr19
34811589
34814345
-
AL021707.2
chr22
38667585
38681847
-
AL355075.4
chr14
20343048
20343685
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.