Entry Detail


General Information

Database ID:exR0510907
RNA Name:ACTR3B
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):152759749End Site(bp):152855378
External Links:ENSG00000133627



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ASH1L
chr1
155335268
155562807
-
RPL27A
chr11
8682788
8714759
+
AC010422.3
chr19
12643831
12648397
-
CNIH4
chr1
224356858
224379459
+
GAB2
chr11
78215293
78418348
-
POU5F1
chr6
31164337
31180731
-
SPOUT1
chr9
128819651
128829794
-
RNF40
chr16
30761745
30776307
+
TRIM14
chr9
98069275
98119222
-
EEF2
chr19
3976056
3985463
-
IPO7
chr11
9384652
9448127
+
RPS12
chr6
132814569
132817564
+
TRIM26
chr6
30184455
30213427
-
SLC25A37
chr8
23528956
23575463
+
HSP90AB1
chr6
44246166
44253888
+
DAXX
chr6
33318558
33323016
-
PLS3
chrX
115561174
115650861
+
MTFR2
chr6
136231024
136250335
-
GSTK1
chr7
143244093
143270854
+
SLC39A1
chr1
153959099
153968184
-
EIF5A
chr17
7306999
7312463
+
SRSF4
chr1
29147743
29181900
-
EIF5B
chr2
99337371
99401326
+
UBR5
chr8
102252273
102412759
-
ZNF638
chr2
71276561
71435069
+
STX7
chr6
132445867
132513198
-
ALG10B
chr12
38316762
38329721
+
INCENP
chr11
62123998
62153169
+
EIF3L
chr22
37848868
37889407
+
RBBP7
chrX
16839283
16870414
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL022311.1
chr22
37876148
37895563
+
LINC00963
chr9
129476946
129513687
+
LINC01315
chr22
42364390
42369284
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.