Entry Detail


General Information

Database ID:exR0510908
RNA Name:ACTR5
RNA Type:mRNA
Chromosome:chr20
Starnd:+
Coordinate:
Start Site(bp):38748460End Site(bp):38772520
External Links:ENSG00000101442



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ATP5PF
chr21
25716503
25735673
-
DPP3
chr11
66480013
66509657
+
FUS
chr16
31180110
31194871
+
HNRNPA1
chr12
54280193
54287088
+
IGF2
chr11
2129112
2141238
-
MATR3
chr5
139273752
139331671
+
MBTPS2
chrX
21839617
21885423
+
NDUFA4
chr7
10931943
10940153
-
OS9
chr12
57693955
57721557
+
RAB1B
chr11
66268590
66277492
+
RAN
chr12
130872037
130877678
+
RPL8
chr8
144789765
144792587
-
RPLP0
chr12
120196699
120201235
-
SLC3A2
chr11
62856102
62888875
+
STMN1
chr1
25884181
25906991
-
TATDN1
chr8
124488485
124539458
-
USP3
chr15
63504511
63594640
+
ZNF618
chr9
113876282
114056591
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AP000233.2
chr21
25095022
25103670
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.