Entry Detail


General Information

Database ID:exR0510909
RNA Name:ACTR6
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):100199122End Site(bp):100241865
External Links:ENSG00000075089



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ANKFY1
chr17
4163821
4263995
-
DDX24
chr14
94048287
94081212
-
AP002990.1
chr11
62559603
62591531
-
CD52
chr1
26317958
26320523
+
HNRNPC
chr14
21209136
21269494
-
RPS23
chr5
82273320
82278396
-
NAGK
chr2
71064344
71079808
+
EEF1G
chr11
62559596
62574086
-
RPL13
chr16
89560657
89566828
+
IGF2
chr11
2129112
2141238
-
UBE2D3
chr4
102794383
102868896
-
CD81
chr11
2376177
2397419
+
VSIG10
chr12
118063593
118136026
-
TMEM123
chr11
102396332
102470384
-
ACTB
chr7
5527148
5563784
-
GYG2
chrX
2828822
2882820
+
RAB35
chr12
120095099
120117502
-
NSUN5
chr7
73302516
73308826
-
HLA-C
chr6
31268749
31272130
-
ATP6AP2
chrX
40579372
40606848
+
FTH1
chr11
61959718
61967634
-
MTRNR2L12
chr3
96617188
96618236
-
ADH5
chr4
99070978
99088801
-
CLEC2D
chr12
9664969
9699553
+
NONO
chrX
71283192
71301168
+
RPS7
chr2
3575260
3580920
+
ZNF90
chr19
20077994
20127076
+
SLAMF1
chr1
160608106
160647295
-
ST8SIA1
chr12
22063773
22437041
-
YIPF3
chr6
43511832
43516985
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-6747-3p
chr11
62567011
62567031
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
LINC02539
chr6
137730170
137792835
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.