Entry Detail


General Information

Database ID:exR0510910
RNA Name:ACTR8
RNA Type:mRNA
Chromosome:chr3
Starnd:-
Coordinate:
Start Site(bp):53867066End Site(bp):53882152
External Links:ENSG00000113812



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
RNF167
chr17
4940008
4945222
+
ZDHHC4
chr7
6577434
6589374
+
UTP6
chr17
31860904
31901708
-
VMP1
chr17
59707192
59842255
+
XPO5
chr6
43522334
43576038
-
WFS1
chr4
6269849
6303265
+
MT-ATP6
chrMT
8527
9207
+
FTL
chr19
48965309
48966879
+
CHPT1
chr12
101696947
101744140
+
EDARADD
chr1
236348257
236502915
+
PAICS
chr4
56435741
56464579
+
DENND4B
chr1
153929501
153946718
-
EIF1AX
chrX
20124525
20141838
-
CLTB
chr5
176392455
176416569
-
HLA-E
chr6
30489509
30494194
+
LSM12
chr17
44034328
44067619
-
IGF2BP1
chr17
48997385
49056145
+
TRAP1
chr16
3651639
3717553
-
CD81
chr11
2376177
2397419
+
OAZ1
chr19
2269509
2273490
+
QPRT
chr16
29663279
29698699
+
MYO9B
chr19
17075781
17214537
+
DCAF15
chr19
13952492
13961449
+
HLA-B
chr6
31269491
31357188
-
ACTN4
chr19
38647649
38731589
+
RALGPS2
chr1
178725147
178921841
+
STRBP
chr9
123109500
123268586
-
ENO2
chr12
6913745
6923698
+
PCYT1B
chrX
24558087
24672677
-
CTNND1
chr11
57753243
57819546
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012313.3
chr19
58346854
58362751
-
LINC00294
chr11
33076149
33079454
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.