Entry Detail


General Information

Database ID:exR0510916
RNA Name:ACVR2A
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):147844517End Site(bp):147930826
External Links:ENSG00000121989



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL133352.1
chr10
100505628
100529881
-
AREL1
chr14
74653437
74713108
-
CHST8
chr19
33621953
33773509
+
DDX17
chr22
38483438
38507660
-
GOLGA4
chr3
37243177
37366751
+
GRK3
chr22
25564675
25729294
+
MAGT1
chrX
77826364
77895593
-
NDUFB8
chr10
100523740
100530000
-
PRKDC
chr8
47773111
47960178
-
RPL3
chr22
39312882
39320389
-
STEAP3
chr2
119223831
119265652
+
TM9SF3
chr10
96518110
96587452
-
TRIM13
chr13
49995888
50020481
+
TSPYL2
chrX
53082367
53088540
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC022211.2
chr17
75145261
75146546
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.