Entry Detail


General Information

Database ID:exR0510941
RNA Name:ADAM8
RNA Type:mRNA
Chromosome:chr10
Starnd:-
Coordinate:
Start Site(bp):133262420End Site(bp):133276868
External Links:ENSG00000151651



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABLIM1
chr10
114431113
114768061
-
AC007192.1
chr19
18153158
18178117
+
ACLY
chr17
41866917
41930542
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
AP1B1
chr22
29327680
29423179
-
ASCC2
chr22
29788609
29838304
-
AVL9
chr7
32495426
32588726
+
BIRC5
chr17
78214186
78225636
+
CAND1
chr12
67269358
67319953
+
DCAF7
chr17
63550477
63594279
+
EBI3
chr19
4229523
4237528
+
EEF1B2
chr2
206159585
206162928
+
HNRNPK
chr9
83968083
83980616
-
IFI30
chr19
18173162
18178117
+
IGF2
chr11
2129112
2141238
-
KIF1C
chr17
4997950
5028401
+
LRFN4
chr11
66856647
66860475
+
MSL3
chrX
11758159
11775772
+
OR4K15
chr14
19975444
19976659
+
PANK4
chr1
2508537
2526611
-
PTGES2
chr9
128120693
128128462
-
RABEP2
chr16
28904421
28936526
-
RPL35A
chr3
197950190
197956610
+
RPS9
chr19
54200809
54249003
+
SLC7A5
chr16
87830023
87869507
-
TFDP1
chr13
113584721
113641473
+
TNPO2
chr19
12699194
12724011
-
TUBGCP2
chr10
133278630
133312337
-
ZFAT
chr8
134477788
134713049
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL359924.1
chr1
237862175
237928321
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.