Entry Detail


General Information

Database ID:exR0510945
RNA Name:ADAMTS10
RNA Type:mRNA
Chromosome:chr19
Starnd:-
Coordinate:
Start Site(bp):8580240End Site(bp):8610735
External Links:ENSG00000142303



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010422.3
chr19
12643831
12648397
-
ALDOA
chr16
30064164
30070457
+
ATXN2L
chr16
28823035
28837237
+
BIN1
chr2
127048027
127107288
-
CD59
chr11
33703010
33736491
-
HDDC3
chr15
90929964
90935196
-
HNRNPDL
chr4
82422564
82430408
-
HSP90AB1
chr6
44246166
44253888
+
LAPTM4B
chr8
97775057
97853013
+
LARGE1
chr22
33162226
33922841
-
MTOR
chr1
11106535
11262551
-
PTMA
chr2
231706895
231713541
+
RPL18A
chr19
17859910
17864153
+
TPI1
chr12
6867119
6870948
+
TSPAN4
chr11
842812
867116
+
TUBB
chr6
30720352
30725426
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.