Entry Detail


General Information

Database ID:exR0510949
RNA Name:ADAMTS17
RNA Type:mRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):99971437End Site(bp):100342005
External Links:ENSG00000140470



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC022384.1
chr3
10249372
10285796
+
ATXN7L3
chr17
44191805
44200113
-
BRD4
chr19
15235519
15332545
-
E2F2
chr1
23506438
23531233
-
EIF4G3
chr1
20806292
21176888
-
ERCC1
chr19
45407333
45478828
-
FUBP3
chr9
130578965
130638352
+
LAMA3
chr18
23689443
23956222
+
LAMA5
chr20
62307955
62367312
-
MAP1B
chr5
72107234
72209565
+
NCOR1
chr17
16029157
16218185
-
PKN1
chr19
14433053
14471867
+
PTPRU
chr1
29236516
29326813
+
SELENOS
chr15
101270817
101277500
-
TATDN2
chr3
10248023
10281218
+
TICRR
chr15
89575469
89631056
+
TMEM151B
chr6
44270450
44307506
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.