Entry Detail


General Information

Database ID:exR0510957
RNA Name:ADAMTS7
RNA Type:mRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):78759206End Site(bp):78811464
External Links:ENSG00000136378



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CCT7
chr2
73233420
73253021
+
CHD4
chr12
6570082
6614524
-
CMTM3
chr16
66603874
66613892
+
EEF2
chr19
3976056
3985463
-
ENOPH1
chr4
82430590
82461177
+
FADS1
chr11
61799627
61829318
-
GNAI2
chr3
50226292
50259362
+
HEY1
chr8
79764010
79767857
-
HSP90AB1
chr6
44246166
44253888
+
LSS
chr21
46188141
46228824
-
MEIS3
chr19
47403124
47419527
-
MORF4L1
chr15
78810487
78898139
+
NXN
chr17
799310
979776
-
OLFML2A
chr9
124777133
124814885
+
PABPC1
chr8
100685816
100722809
-
POU5F1
chr6
31164337
31180731
-
PPP1R13L
chr19
45379638
45406349
-
SMG1
chr16
18804853
18926454
-
SNX17
chr2
27370496
27377535
+
TPM3
chr1
154155304
154194648
-
TRAF7
chr16
2155698
2178129
+
WWC2
chr4
183099257
183320777
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
SNHG15
chr7
44983023
44986961
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.