Entry Detail


General Information

Database ID:exR0510965
RNA Name:ADAP1
RNA Type:mRNA
Chromosome:chr7
Starnd:-
Coordinate:
Start Site(bp):897900End Site(bp):955407
External Links:ENSG00000105963



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
COX19
chr7
898778
975549
-
CYC1
chr8
144095039
144097525
+
ERC1
chr12
990509
1495933
+
HNRNPD
chr4
82352498
82374503
-
ITGAV
chr2
186590056
186680901
+
JMJD8
chr16
681670
684528
-
KDM4B
chr19
4969113
5153598
+
MCRIP2
chr16
636817
648474
+
NUP93
chr16
56730118
56850286
+
PHLDA1
chr12
76025447
76033932
-
RAC1
chr7
6374527
6403967
+
RPS20
chr8
56067295
56074581
-
TIMM9
chr14
58408495
58427531
-
TMEM165
chr4
55395957
55453397
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.