Entry Detail


General Information

Database ID:exR0510968
RNA Name:ADARB1
RNA Type:mRNA
Chromosome:chr21
Starnd:+
Coordinate:
Start Site(bp):45073853End Site(bp):45226560
External Links:ENSG00000197381



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
UBB
chr17
16380798
16382745
+
LBHD1
chr11
62662817
62672255
-
TNPO2
chr19
12699194
12724011
-
TXNRD2
chr22
19875517
19941820
-
TMEM131
chr2
97756333
97995948
-
EXOSC10
chr1
11066618
11099869
-
IFT140
chr16
1510427
1612072
-
ZFR
chr5
32354350
32444740
-
RPL37A
chr2
216498825
216579180
+
RAC2
chr22
37225270
37244448
-
IGF1R
chr15
98648539
98964530
+
CAD
chr2
27217369
27243943
+
WDR45B
chr17
82614562
82648553
-
HMGA1
chr6
34236873
34246231
+
SLC9A3R1
chr17
74748628
74769353
+
PSMA4
chr15
78540405
78552417
+
MYCN
chr2
15940550
15947007
+
MAPK12
chr22
50245450
50261716
-
RPS14
chr5
150442635
150449739
-
PIP4K2C
chr12
57591174
57603418
+
PIP5K1A
chr1
151197949
151249536
+
SYNJ2BP-COX16
chr14
70326064
70417074
-
AC120114.4
chr16
29817239
29830627
+
RANBP1
chr22
20115938
20127355
+
COASY
chr17
42561467
42566277
+
HNRNPU
chr1
244840638
244864560
-
GFOD2
chr16
67674531
67719339
-
SPON1
chr11
13962723
14268133
+
COX16
chr14
70325081
70416984
-
AUTS2
chr7
69598296
70793506
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-17-5p
chr13
91350618
91350640
+
hsa-miR-20a-5p
chr13
91351072
91351094
+
hsa-miR-93-5p
chr7
100093815
100093837
-
hsa-miR-106a-5p
chrX
134170244
134170266
-
hsa-miR-301a-3p
chr17
59151149
59151171
-
hsa-miR-20b-5p
chrX
134169850
134169872
-
hsa-miR-512-3p
chr19
53666729
53666750
+
hsa-miR-454-3p
chr17
59137787
59137809
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
SNHG7
chr9
136721366
136728184
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.