Entry Detail


General Information

Database ID:exR0510970
RNA Name:ADAT1
RNA Type:mRNA
Chromosome:chr16
Starnd:-
Coordinate:
Start Site(bp):75596981End Site(bp):75623300
External Links:ENSG00000065457



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BFAR
chr16
14632931
14669236
+
CD22
chr19
35319261
35347361
+
CD48
chr1
160678746
160711831
-
CFDP1
chr16
75293698
75433503
-
CREB3L2
chr7
137874979
138002086
-
FUT11
chr10
73772276
73780251
+
HNRNPM
chr19
8444767
8489114
+
IGF2
chr11
2129112
2141238
-
KCNC3
chr19
50311937
50333515
-
KMT2B
chr19
35717973
35738878
+
MAEA
chr4
1289887
1340147
+
METRN
chr16
715118
719655
+
NME1-NME2
chr17
51153590
51171744
+
NME2
chr17
51165435
51171747
+
NT5DC2
chr3
52524385
52535054
-
PAK1
chr11
77321707
77474635
-
RPP14
chr3
58306247
58324695
+
STT3A
chr11
125591712
125625215
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC025287.1
chr16
75541399
75608445
-
KCNQ1OT1
chr11
2608328
2699994
-
MALAT1
chr11
65497688
65506516
+
ZNF710-AS1
chr15
90074512
90082207
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.