Entry Detail


General Information

Database ID:exR0510971
RNA Name:ADAT2
RNA Type:mRNA
Chromosome:chr6
Starnd:-
Coordinate:
Start Site(bp):143422832End Site(bp):143450695
External Links:ENSG00000189007



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC011511.4
chr19
10315471
10320678
-
AC118549.1
chr1
77562416
77683419
-
AP002990.1
chr11
62559603
62591531
-
ATP5F1B
chr12
56638175
56645984
-
B4GALT6
chr18
31622247
31685836
-
DDI2
chr1
15617458
15669044
+
DUSP1
chr5
172768096
172771195
-
EEF1A1
chr6
73515750
73523797
-
EEF1G
chr11
62559596
62574086
-
FBXO31
chr16
87326987
87392142
-
FBXO41
chr2
73254682
73284431
-
FNDC3B
chr3
172039578
172401669
+
GLO1
chr6
38675925
38703145
-
KNTC1
chr12
122527246
122626396
+
LEPROT
chr1
65420587
65436007
+
PSME1
chr14
24136163
24138967
+
RAVER1
chr19
10316212
10333638
-
RPS6KB2
chr11
67428460
67435401
+
RSC1A1
chr1
15659869
15661722
+
SRSF10
chr1
23964347
23980927
-
YWHAQ
chr2
9583967
9630997
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-18a-5p
chr13
91350756
91350778
+
hsa-miR-18b-5p
chrX
134170084
134170106
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.