Entry Detail


General Information

Database ID:exR0510972
RNA Name:ADAT3
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):1905399End Site(bp):1913447
External Links:ENSG00000213638



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
STRN3
chr14
30893799
31026401
-
DBN1
chr5
177456608
177474401
-
NUDT19
chr19
32691961
32713796
+
STARD9
chr15
42575606
42720998
+
KRT18
chr12
52948871
52952906
+
JUND
chr19
18279694
18281622
-
MLLT6
chr17
38705273
38729795
+
TMEM256-PLSCR3
chr17
7389734
7404097
-
LARP1
chr5
154712843
154817605
+
SYMPK
chr19
45815410
45863194
-
SLC9A3R1
chr17
74748628
74769353
+
EXOSC2
chr9
130693721
130704894
+
TMEM132A
chr11
60924463
60937159
+
HNRNPAB
chr5
178204533
178211163
+
DHX38
chr16
72093613
72112912
+
HNRNPK
chr9
83968083
83980616
-
PLSCR3
chr17
7389727
7394842
-
RPS28
chr19
8321158
8323340
+
C5AR1
chr19
47290023
47322066
+
DZIP1
chr13
95578202
95644703
-
CIC
chr19
42268537
42295797
+
ZNF721
chr4
425815
499156
-
SRSF4
chr1
29147743
29181900
-
SIRPA
chr20
1894167
1940592
+
SCAMP4
chr19
1905372
1926013
+
ARAP1
chr11
72685069
72793599
-
RAN
chr12
130872037
130877678
+
HTT
chr4
3041422
3243960
+
PKMYT1
chr16
2968024
2980479
-
CYB5R3
chr22
42617840
42649392
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
MIRLET7BHG
chr22
46053869
46113928
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.