Entry Detail


General Information

Database ID:exR0510974
RNA Name:ADCK2
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):140672945End Site(bp):140696261
External Links:ENSG00000133597



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
TXNIP
chr1
145992435
145996579
-
RPL13A
chr19
49487554
49492308
+
RPS25
chr11
119015712
119018691
-
RBM47
chr4
40423267
40630875
-
INPPL1
chr11
72223701
72239147
+
CCAR2
chr8
22604632
22621514
+
PLCXD1
chrX
276322
303356
+
ITGB2
chr21
44885953
44931989
-
NDUFV1
chr11
67605653
67612554
+
POGK
chr1
166839447
166856344
+
MTRNR2L12
chr3
96617188
96618236
-
POC1A
chr3
52075226
52154690
-
HBS1L
chr6
134960378
135103056
-
RPL27A
chr11
8682788
8714759
+
RPL35
chr9
124857880
124861981
-
NYNRIN
chr14
24399003
24419283
+
PTMA
chr2
231706895
231713541
+
TUBA1C
chr12
49188736
49274603
+
SOX11
chr2
5692384
5701385
+
LARP4B
chr10
806914
931705
-
NDUFB2
chr7
140690777
140722790
+
HNRNPA2B1
chr7
26173057
26201529
-
RBMX
chrX
136848004
136880764
-
RPS3
chr11
75399515
75422280
+
SPEN
chr1
15836095
15940456
+
COX10
chr17
14069490
14231736
+
ABCA2
chr9
137007234
137028922
-
CSE1L
chr20
49046246
49096960
+
DDHD2
chr8
38225218
38275558
+
LSM12
chr17
44034328
44067619
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.