Entry Detail


General Information

Database ID:exR0510976
RNA Name:ADCY1
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):45574140End Site(bp):45723116
External Links:ENSG00000164742



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HLA-A
chr6
29941260
29945884
+
RBMXL1
chr1
88979456
88992960
-
CTTN
chr11
70398404
70436584
+
SCYL1
chr11
65525077
65538704
+
FP565260.1
chr21
5130871
5154658
-
ICE1
chr5
5420664
5490220
+
GNAS
chr20
58839718
58911192
+
NFATC2IP
chr16
28950807
28967097
+
SV2A
chr1
149903318
149917844
-
GLRX3
chr10
130136391
130184521
+
LAMA5
chr20
62307955
62367312
-
MFSD1
chr3
158732198
158829719
+
TMEM185A
chrX
149596556
149631912
-
UBXN4
chr2
135741734
135785056
+
C6orf62
chr6
24704861
24719998
-
SZRD1
chr1
16352575
16398145
+
PWP2
chr21
44107373
44131181
+
MBP
chr18
76978827
77133683
-
ATP5MC2
chr12
53632726
53677408
-
KLF2
chr19
16324817
16327874
+
GAPDH
chr12
6534512
6538374
+
KAT2A
chr17
42113111
42121367
-
HUWE1
chrX
53532096
53686728
-
RAB5A
chr3
19947097
19985175
+
PHB2
chr12
6965327
6970753
-
MARCKS
chr6
113857345
113863475
+
SUMO3
chr21
44805617
44818779
-
NCOA6
chr20
34689097
34825651
-
FBRSL1
chr12
132489551
132585188
+
LAMB1
chr7
107923799
108003187
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
LINC00665
chr19
36313067
36331770
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.