Entry Detail


General Information

Database ID:exR0510983
RNA Name:ADCY7
RNA Type:mRNA
Chromosome:chr16
Starnd:+
Coordinate:
Start Site(bp):50246137End Site(bp):50318135
External Links:ENSG00000121281



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACTG1
chr17
81509971
81523847
-
ADCY4
chr14
24318349
24335093
-
CNTROB
chr17
7932101
7949920
+
FTL
chr19
48965309
48966879
+
GLUD1
chr10
87050202
87094843
-
GSTP1
chr11
67583742
67586656
+
HSPE1
chr2
197500140
197503449
+
MRPS6
chr21
34073224
34143034
+
PNMA8A
chr19
46466491
46471563
-
RPL4
chr15
66498015
66524532
-
RPL7A
chr9
133348218
133351426
+
SBNO2
chr19
1107637
1174268
-
SLC5A3
chr21
34073578
34106260
+
SRGN
chr10
69088103
69104805
+
SYNGR2
chr17
78168558
78173527
+
TMEM189-UBE2V1
chr20
50081124
50153637
-
TPT1
chr13
45333471
45341370
-
TTC38
chr22
46267961
46294008
+
UBE2V1
chr20
50081124
50115959
-
ZFP36L1
chr14
68787660
68796253
-
ZHX3
chr20
41178448
41317672
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AP000317.2
chr21
34073592
34360033
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.