Entry Detail


General Information

Database ID:exR0510997
RNA Name:ADI1
RNA Type:mRNA
Chromosome:chr2
Starnd:-
Coordinate:
Start Site(bp):3497366End Site(bp):3519531
External Links:ENSG00000182551



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ENO3
chr17
4948092
4957131
+
GNL2
chr1
37566816
37595937
-
ZNF485
chr10
43606419
43617904
+
CYTH2
chr19
48469208
48482314
+
APP
chr21
25880550
26171128
-
RPL36
chr19
5674947
5691875
+
SLC44A2
chr19
10602457
10644557
+
PAICS
chr4
56435741
56464579
+
TMSB4X
chrX
12975110
12977227
+
RPS14
chr5
150442635
150449739
-
SERPING1
chr11
57597387
57614848
+
STC2
chr5
173314713
173329503
-
LIMS1
chr2
108534355
108687246
+
SMARCA4
chr19
10960825
11079426
+
TTLL6
chr17
48762235
48817214
-
MORF4L2
chrX
103675496
103688158
-
ADD3
chr10
109996368
110135565
+
SLC11A2
chr12
50979401
51028566
-
RWDD3
chr1
95234210
95247225
+
HNRNPAB
chr5
178204533
178211163
+
QPRT
chr16
29663279
29698699
+
TCF7L1
chr2
85133392
85310387
+
CIZ1
chr9
128161251
128204383
-
SFSWAP
chr12
131711081
131799737
+
MFN1
chr3
179347709
179394936
+
OCIAD1
chr4
48805212
48861817
+
CCT7
chr2
73233420
73253021
+
VANGL2
chr1
160400564
160428670
+
U2AF1L5
chr21
6484623
6499261
-
SNX3
chr6
108211222
108261246
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009446.1
chr8
71675300
71702786
+
AC022400.6
chr10
73703735
73713581
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.