Entry Detail


General Information

Database ID:exR0511001
RNA Name:ADK
RNA Type:mRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):74151202End Site(bp):74709963
External Links:ENSG00000156110



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CLTC
chr17
59619689
59696956
+
CORO1C
chr12
108645109
108731596
-
BCL2L1
chr20
31664452
31723989
-
C12orf57
chr12
6942978
6946003
+
IFI6
chr1
27666064
27672198
-
RAB11FIP3
chr16
425649
523011
+
GDI2
chr10
5765223
5842132
-
GRWD1
chr19
48445841
48457022
+
BCKDHA
chr19
41397808
41425002
+
DGKZ
chr11
46332905
46380554
+
IGF2
chr11
2129112
2141238
-
PRMT1
chr19
49675786
49689029
+
GJA1
chr6
121435595
121449727
+
KRT19
chr17
41523617
41528308
-
HLA-DPA1
chr6
33064569
33080775
-
EIF3E
chr8
108201216
108435333
-
INO80B-WBP1
chr2
74455088
74460884
+
TRIO
chr5
14143342
14532128
+
MTRNR2L8
chr11
10507894
10509186
-
PTPN1
chr20
50510321
50585241
+
ZNF664
chr12
123971845
124015439
+
MRPL35
chr2
86199355
86213790
+
CCNG1
chr5
163437569
163446151
+
STAU1
chr20
49113339
49188367
-
NBEAL1
chr2
203014879
203226378
+
HMGN3
chr6
79201245
79234738
-
RPS27L
chr15
63125872
63158021
-
ENO1
chr1
8861000
8879190
-
UBE2J2
chr1
1253909
1273885
-
TMED7
chr5
115613210
115632992
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC132217.1
chr11
2129121
2129964
-
AD000090.1
chr19
35557956
35581954
+
IGF2-AS
chr11
2140501
2148666
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.