Entry Detail


General Information

Database ID:exR0511004
RNA Name:ADNP
RNA Type:mRNA
Chromosome:chr20
Starnd:-
Coordinate:
Start Site(bp):50888916End Site(bp):50931437
External Links:ENSG00000101126



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HNRNPA3
chr2
177212563
177223958
+
GRPEL1
chr4
7058895
7068064
-
SNRPA
chr19
40750637
40765389
+
IL9R
chrX
155997581
156010817
+
RPLP0
chr12
120196699
120201235
-
COG8
chr16
69320140
69339667
-
CREBRF
chr5
173056352
173139284
+
RREB1
chr6
7107597
7251980
+
LMO2
chr11
33858576
33892076
-
HDGF
chr1
156742109
156766925
-
TUBA1B
chr12
49127782
49131397
-
ZFAND3
chr6
37819727
38154624
+
CUL9
chr6
43182184
43224587
+
SLC39A10
chr2
195575977
195737702
+
GATD1
chr11
767220
777488
-
POLR2B
chr4
56977722
57031158
+
HPS5
chr11
18278668
18322198
-
KDM3B
chr5
138352685
138437028
+
CCT3
chr1
156308968
156367873
-
ACOT9
chrX
23701055
23766475
-
MTCH1
chr6
36968141
36986298
-
LRP11
chr6
149818757
149864359
-
LMAN1
chr18
59327823
59359265
-
EIF4E2
chr2
232550674
232583644
+
CBL
chr11
119206298
119313926
+
ATP5MC3
chr2
175176258
175184607
-
C18orf25
chr18
46173553
46266992
+
MAP7D1
chr1
36155579
36180849
+
HMGA1
chr6
34236873
34246231
+
PRMT3
chr11
20387558
20509338
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-17-5p
chr13
91350618
91350640
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC023509.1
chr12
53441741
53467528
+
AJ271736.1
chrX
156004218
156022236
+
AC079949.1
chr12
127142029
127146532
-
MALAT1
chr11
65497688
65506516
+
MIR17HG
chr13
91347820
91354579
+
TUG1
chr22
30969245
30979395
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.