Entry Detail


General Information

Database ID:exR0511005
RNA Name:ADNP2
RNA Type:mRNA
Chromosome:chr18
Starnd:+
Coordinate:
Start Site(bp):80109262End Site(bp):80147523
External Links:ENSG00000101544



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
PWP2
chr21
44107373
44131181
+
USP14
chr18
158383
214629
+
ERBB2
chr17
39687914
39730426
+
EEF2
chr19
3976056
3985463
-
MT-ND2
chrMT
4470
5511
+
RPL26
chr17
8377516
8383213
-
TOM1L2
chr17
17843511
17972422
-
DSC2
chr18
31058840
31102522
-
ARID4B
chr1
235131634
235328219
-
FBXO42
chr1
16246840
16352480
-
PEBP1
chr12
118136124
118145584
+
CDC42EP3
chr2
37641882
37738468
-
NOMO3
chr16
16232528
16294811
+
PTMA
chr2
231706895
231713541
+
ACTA2
chr10
88935074
88991339
-
ACTB
chr7
5527148
5563784
-
PRKCI
chr3
170222424
170305977
+
TOMM70
chr3
100363431
100401089
-
FP565260.1
chr21
5130871
5154658
-
RPS20
chr8
56067295
56074581
-
SH3GLB1
chr1
86704570
86748184
+
GRID2IP
chr7
6497462
6551436
-
COL4A2
chr13
110305812
110513209
+
PGP
chr16
2211593
2214840
-
CERS6
chr2
168455862
168775137
+
NAP1L1
chr12
76036585
76084958
-
ALDOA
chr16
30064164
30070457
+
RPA2
chr1
27891524
27914746
-
ITM2C
chr2
230864639
230879248
+
CALR
chr19
12938578
12944489
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4508
chr15
23562107
23562123
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007218.1
chr16
9666885
9676843
-
AC135178.2
chr17
8318088
8318712
-
AL391294.1
chrX
81000150
81004217
-
HOXA-AS2
chr7
27107777
27134302
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.