Entry Detail


General Information

Database ID:exR0511008
RNA Name:ADORA2A
RNA Type:mRNA
Chromosome:chr22
Starnd:+
Coordinate:
Start Site(bp):24417879End Site(bp):24442357
External Links:ENSG00000128271



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
TUBA1A
chr12
49184795
49189080
-
ILK
chr11
6603708
6610874
+
RPL23A
chr17
28719985
28724359
+
TUB
chr11
8019244
8106112
+
GABARAP
chr17
7240008
7242449
-
RETREG2
chr2
219176225
219185475
+
RPS3
chr11
75399515
75422280
+
LMNA
chr1
156082573
156140089
+
SPECC1L
chr22
24270817
24417739
+
IFI30
chr19
18173162
18178117
+
NFKB2
chr10
102394110
102402524
+
RPL9
chr4
39452521
39458949
-
MX1
chr21
41420304
41459214
+
EIF4B
chr12
53006158
53042209
+
LRFN4
chr11
66856647
66860475
+
CTSH
chr15
78921058
78949574
-
CHCHD3
chr7
132784870
133082090
-
ITGB1
chr10
32900318
33005792
-
MTPN
chr7
135926760
135977359
-
IFFO1
chr12
6538375
6556083
-
CLK3
chr15
74598500
74645414
+
RPL3
chr22
39312882
39320389
-
P4HB
chr17
81843161
81860624
-
RPS16
chr19
39433137
39435949
-
VAMP5
chr2
85584431
85593406
+
SPECC1L-ADORA2A
chr22
24270898
24442356
+
TMSB4X
chrX
12975110
12977227
+
MCM2
chr3
127598410
127622436
+
ACTG1
chr17
81509971
81523847
-
EIF3D
chr22
36510855
36529184
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL121832.3
chr20
62402236
62405935
-
AL137127.1
chr1
19072110
19075511
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.