Entry Detail


General Information

Database ID:exR0511052
RNA Name:AGGF1
RNA Type:mRNA
Chromosome:chr5
Starnd:+
Coordinate:
Start Site(bp):77029251End Site(bp):77065234
External Links:ENSG00000164252



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ASPM
chr1
197084127
197146694
-
RPL27A
chr11
8682788
8714759
+
PGK1
chrX
77910739
78129295
+
TUBA1B
chr12
49127782
49131397
-
EIF5A
chr17
7306999
7312463
+
FP565260.6
chr21
5155499
5165472
-
MYL6
chr12
56158161
56163496
+
FP565260.2
chr21
5116343
5133805
-
ESRP1
chr8
94641074
94707466
+
SUB1
chr5
32531633
32604079
+
BZW2
chr7
16646131
16706523
+
ACTA1
chr1
229431245
229434098
-
B2M
chr15
44711487
44718877
+
NEDD4L
chr18
58044226
58401540
+
HLA-A
chr6
29941260
29945884
+
MARCKSL1
chr1
32333839
32336233
-
RPS9
chr19
54200809
54249003
+
AC008581.2
chr5
77030902
77152155
+
KIFC3
chr16
57758217
57863053
-
SMC4
chr3
160399274
160434954
+
PRRC1
chr5
127517609
127555089
+
TCEAL4
chrX
103576231
103587736
+
PPP2R5B
chr11
64917553
64934475
+
ERAL1
chr17
28855010
28861061
+
PBX1
chr1
164555584
164899296
+
ID1
chr20
31605283
31606515
+
CCPG1
chr15
55340032
55408510
-
RPL23A
chr17
28719985
28724359
+
ACTN1
chr14
68874143
68979440
-
MIF
chr22
23894383
23895227
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
FGD5-AS1
chr3
14920347
14948424
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.