Entry Detail


General Information

Database ID:exR0511054
RNA Name:AGL
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):99850361End Site(bp):99924023
External Links:ENSG00000162688



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
FSD1
chr19
4304598
4323843
+
ATP5F1B
chr12
56638175
56645984
-
MRPL16
chr11
59806140
59810778
-
CTPS1
chr1
40979688
41012565
+
MARCKSL1
chr1
32333839
32336233
-
ERCC6
chr10
49454470
49539538
-
APP
chr21
25880550
26171128
-
CRLS1
chr20
6006093
6040053
+
NAT10
chr11
34105617
34147670
+
EEF1A1
chr6
73515750
73523797
-
PTOV1
chr19
49850735
49860744
+
NUCKS1
chr1
205712822
205750182
-
KLHL15
chrX
23983720
24027186
-
PPIA
chr7
44796680
44824564
+
RPS8
chr1
44775251
44778779
+
POLD3
chr11
74493851
74669117
+
ANXA7
chr10
73375101
73414076
-
TBKBP1
chr17
47694081
47712050
+
CARD10
chr22
37490362
37519542
-
IQSEC1
chr3
12897043
13283281
-
BEX4
chrX
103215108
103217246
+
MRPL13
chr8
120380761
120445402
-
CIAPIN1
chr16
57428187
57447420
-
MIGA2
chr9
129036621
129072082
+
KIF3C
chr2
25926598
25982749
-
DTL
chr1
212035553
212107400
+
KHDRBS1
chr1
32013868
32060850
+
UHMK1
chr1
162497251
162529631
+
AURKAIP1
chr1
1373730
1375495
-
PARP1
chr1
226360691
226408093
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-302b-3p
chr4
112648489
112648511
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
LINC00910
chr17
43338741
43389199
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.