Entry Detail


General Information

Database ID:exR0511084
RNA Name:AIDA
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):222668013End Site(bp):222713210
External Links:ENSG00000186063



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
EEF1A1
chr6
73515750
73523797
-
RPS6
chr9
19375715
19380236
-
SALL1
chr16
51135975
51151367
-
PDIA6
chr2
10783391
10837977
-
STRN4
chr19
46719511
46746994
-
RARRES2
chr7
150338317
150341662
-
SH2B2
chr7
102285091
102321711
+
TMEM106C
chr12
47963569
47968878
+
HLA-B
chr6
31269491
31357188
-
URI1
chr19
29923644
30016612
+
PHGDH
chr1
119648411
119744226
+
UBXN1
chr11
62676498
62679117
-
EMD
chrX
154379273
154381523
+
MRPL13
chr8
120380761
120445402
-
SMAD4
chr18
51028394
51085045
+
EIF4G1
chr3
184314495
184335358
+
FEM1B
chr15
68277745
68295862
+
RPL4
chr15
66498015
66524532
-
RAB8B
chr15
63189560
63267776
+
RPL11
chr1
23691742
23696835
+
PAK1IP1
chr6
10694972
10709782
+
MIF
chr22
23894383
23895227
+
EPB41L5
chr2
120013077
120179119
+
ATP2B1
chr12
89588049
89709300
-
ZFP36L2
chr2
43222402
43226606
-
ADAR
chr1
154582057
154628013
-
NSMCE1
chr16
27224994
27268772
-
GPSM1
chr9
136327476
136359605
+
CPNE3
chr8
86514435
86561498
+
AHNAK
chr11
62433542
62556235
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.