Entry Detail


General Information

Database ID:exR0511115
RNA Name:AKNA
RNA Type:mRNA
Chromosome:chr9
Starnd:-
Coordinate:
Start Site(bp):114334156End Site(bp):114394405
External Links:ENSG00000106948



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
TNFAIP3
chr6
137867214
137883312
+
RASGRP3
chr2
33436324
33564750
+
SSR4
chrX
153793516
153798499
+
RPS9
chr19
54200809
54249003
+
RPS19
chr19
41860255
41872925
+
ATP6V1D
chr14
67294371
67360265
-
UBALD2
chr17
76265348
76271298
+
NDUFS4
chr5
53560633
53683338
+
BRMS1
chr11
66337333
66345125
-
ETFB
chr19
51345169
51366418
-
SKP1
chr5
134148935
134177038
-
RPL11
chr1
23691742
23696835
+
ABCC5
chr3
183919934
184017939
-
MLST8
chr16
2204248
2209453
+
RPL13
chr16
89560657
89566828
+
PGRMC2
chr4
128269237
128288829
-
HIKESHI
chr11
86302211
86345943
+
EIF4B
chr12
53006158
53042209
+
ERI2
chr16
20780193
20900349
-
BUB3
chr10
123154402
123170467
+
SHC1
chr1
154962298
154974395
-
GLRX3
chr10
130136391
130184521
+
HLA-DRB1
chr6
32578769
32589848
-
FKBP8
chr19
18531751
18544077
-
ALAS1
chr3
52198086
52214327
+
TUBB
chr6
30720352
30725426
+
ATPAF1
chr1
46632737
46673867
-
HNRNPA2B1
chr7
26173057
26201529
-
PYGO2
chr1
154957026
154963853
-
COX7A2L
chr2
42333546
42425088
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL138895.1
chr9
114396724
114398503
-
LINC00882
chr3
106449775
107240671
-
MIR663AHG
chr20
26167817
26251546
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.